シンポジウム一覧
| 3月26日(日) 10:45～11:45 B会場 仙台国際センター 「会議棟」 2F 大会議室「橘」 | |
| ISMS | |
| 第3回国際創薬シンポジウム ISMS | |
| 3rd International Symposium for Medicinal Sciences | |
| オーガナイザー：Akira OTAKA | |
| ISMS-PL01 | |
| Robot Scientists: Automating Drug Design | |
| Robot Scientists: Automating Drug Design | |
| シンポジスト ： | Ross D. KING |
| 3月26日(日) 13:15～14:15 B会場 仙台国際センター 「会議棟」 2F 大会議室「橘」 | |
| ISMS-PL02 | |
| Recent Advances in cryo-EM: Applications to Drug Discovery | |
| Recent Advances in cryo-EM: Applications to Drug Discovery | |
| シンポジスト ： | Sriram SUBRAMANIAM |
| 3月26日(日) 14:20～17:40 G会場 仙台国際センター 「会議棟」 2F 小会議室4 | |
| 26G-ISMS01 | |
| Unstructured Protein : A New Approach for Drug Discovery | |
| Unstructured Protein : A New Approach for Drug Discovery | |
| シンポジスト ： | ○Takenao ODAGAMI、Yoichiro HIROSE、Yoshimasa IMAMURA、Akira KATOH、Tadashi MISHINA、Hiroyuki KOUJI |
| 26G-ISMS02 | |
| Development of Macrocyclic Peptide Targeting Ebola Glycoprotein | |
| Development of Macrocyclic Peptide Targeting Ebola Glycoprotein | |
| シンポジスト ： | ○Shiori UMEMOTO、Junki MARUYAMA、Ayato TAKADA、Hiroaki SUGA |
| 26G-ISMS03 | |
| Combinatorial Solid-Phase Synthesis and Biological Evaluation of Cyclodepsipeptide Destruxin B as a Negative Regulator for Osteoclast Morphology | |
| Combinatorial Solid-Phase Synthesis and Biological Evaluation of Cyclodepsipeptide Destruxin B as a Negative Regulator for Osteoclast Morphology | |
| シンポジスト ： | ○Hiroshi SATO、Masahito YOSHIDA、Hayato MURASE、Hiroshi NAKAGAWA、Takayuki DOI |
| 26G-ISMS04 | |
| SAR Exploration of Selective Kinase Inhibitors based on the “Head-to-Tail” Approach: Discovery of PI4KIIIα Inhibitors Bearing Diverse Scaffolds | |
| SAR Exploration of Selective Kinase Inhibitors based on the “Head-to-Tail” Approach: Discovery of PI4KIIIα Inhibitors Bearing Diverse Scaffolds | |
| シンポジスト ： | ○Satoru NOJI、Noriyoshi SEKI、Takaki MAEBA、Takayuki SAKAI、Eiichi WATANABE、Katsuya MAEDA、Kyoko FUKUSHIMA、Toru NOGUCHI、Kazuya OGAWA、Yukiyo TOYONAGA、Tamotsu NEGORO、Hisashi KAWASAKI、Makoto SHIOZAKI |
| 26G-ISMS05 | |
| Search for Anti-leukemic Drugs Targeting the Transcription Factor Runx1 by INTENDD | |
| Search for Anti-leukemic Drugs Targeting the Transcription Factor Runx1 by INTENDD | |
| シンポジスト ： | ○Masaaki SHIINA、Shiho BABA、Akiko UCHIYAMA、Chikako OKADA、Takeshi TANAKA、Ken IKEDA、Shigetsugu KAWAKITA、Takao MATSUZAKI、Hirotsugu KOMATSU、Masato HOSODA、Kazuhiro OGATA |
| 26G-ISMS06 | |
| Evaluation of Novel Anti-Dengue Candidates Using In Silico and In Vitro Approaches | |
| Evaluation of Novel Anti-Dengue Candidates Using In Silico and In Vitro Approaches | |
| シンポジスト ： | ○Yu-Shi TIAN、Hitoshi MATSUDA、Xinzhe LIU、Norihito KAWASHITA、Tatsuya TAKAGI |
| 26G-ISMS08 | |
| Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]Pyridazine- based p38 MAP Kinase Inhibitors | |
| Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]Pyridazine- based p38 MAP Kinase Inhibitors | |
| シンポジスト ： | ○Akira KAIEDA、Masashi TAKAHASHI、Takafumi TAKAI、Masayuki GOTO、Takahiro MIYAZAKI、Yuri HORI、Satoko UNNO、Tomohiro KAWAMOTO、Toshimasa TANAKA、Sachiko ITONO、Terufumi TAKAGI、Teruki HAMADA、Mikio SHIRASAKI、Kengo OKADA、Gyorgy SNELL、Ken BRAGSTAD、Bi-Ching SANG、Osamu U |
| 26G-ISMS09 | |
| Flow Chemistry: New Horizons in Chemical Space for the Creation of Next Generation Libraries | |
| Flow Chemistry: New Horizons in Chemical Space for the Creation of Next Generation Libraries | |
| シンポジスト ： | Daniel BLANCO-ANIA、Sagar Ashok GAWADE、Luuk MAARTENSE、Roel VERLEIJSDONK、Remco MERKX、Huib OVAA、Floris RUTJES、Marjon BOLSTER、Luc ZWINKELS、Joeri SCHEIDT、Pauline van MEURS、Jorg BENNINGSHOF、○Norimasa MORITA |
| 26G-ISMS10 | |
| Transition Metal-Free, Tryptophan-Selective Bioconjugation of Proteins | |
| Transition Metal-Free, Tryptophan-Selective Bioconjugation of Proteins | |
| シンポジスト ： | ○Kounosuke OISAKI、Yohei SEKI、Takashi ISHIYAMA、Daisuke SASAKI、Junpei ABE、Yohei SOHMA、Motomu KANAI |
| 26G-ISMS11 | |
| Total Synthesis of Halichondrin A and C | |
| Total Synthesis of Halichondrin A and C | |
| シンポジスト ： | ○Akihiko YAMAMOTO、Atsushi UEDA、Paul BRÉMOND、Paolo S. TISENI、Daisuke KATO、Yoshito KISHI |
| 26G-ISMS12 | |
| Parallel Fluorescent Probe Synthesis Based on the Large-scale Preparation of BODIPY FL Propionic Acid | |
| Parallel Fluorescent Probe Synthesis Based on the Large-scale Preparation of BODIPY FL Propionic Acid | |
| シンポジスト ： | ○Taisuke KATOH、Masato YOSHIKAWA、Takeshi YAMAMOTO、Ryosuke ARAI、Noriyuki NII、Yoshihide TOMATA、Shinkichi SUZUKI、Ryoukichi KOYAMA、Nobuyuki NEGORO、Takatoshi YOGO |
| 26G-ISMS13 | |
| Improvement in Pharmacokinetics and In Vivo Activity of Somatostatin by Chemical Glycosylation | |
| Improvement in Pharmacokinetics and In Vivo Activity of Somatostatin by Chemical Glycosylation | |
| シンポジスト ： | ○Hirofumi OCHIAI、Jun IGARASHI、Hayato SAIJO、Takahiro YAMAMOTO、Yuji NISHIUCHI、Akio KANATANI、Taiji SHIMODA |
| 26G-ISMS14 | |
| Development of an Oxidative Mizoroki-Heck Reaction for Late-stage C-H Functionalization of Complex Molecules and Application to Pharmaceutical Studies | |
| Development of an Oxidative Mizoroki-Heck Reaction for Late-stage C-H Functionalization of Complex Molecules and Application to Pharmaceutical Studies | |
| シンポジスト ： | ○Kenji WATANABE、Amrita DAS、Takumi KIMIJIMA、Tomohiro YAMASHITA、Kazuhide INOUE、Makoto TSUDA、Takashi OHSHIMA |
| 26G-ISMS15 | |
| Functional Characterization of Acetylcholine Receptors in Human Hippocampus-Derived Neurons | |
| Functional Characterization of Acetylcholine Receptors in Human Hippocampus-Derived Neurons | |
| シンポジスト ： | ○Kazuyuki FUKUSHIMA、Kazuto YAMAZAKI、Norimasa MIYAMOTO、Kohei SAWADA |
| 26G-ISMS16 | |
| Analgesic Effect of Novel 11β-HSD1 Inhibitor ASP3662 and its Mechanism of Action in a Spinal Nerve Ligation Model of Neuropathic Pain | |
| Analgesic Effect of Novel 11β-HSD1 Inhibitor ASP3662 and its Mechanism of Action in a Spinal Nerve Ligation Model of Neuropathic Pain | |
| シンポジスト ： | ○Tetsuo KISO、Toshihiro SEKIZAWA、Mina TSUKAMOTO、Junko YARIMIZU、Shuichiro KAKIMOTO |
| 26G-ISMS17 | |
| Atomic-Scale Investigation on Acetaminophen Crystals with Stable and Metastable Phases by Frequency Modulation Atomic Force Microscopy in Aqueous Solution | |
| Atomic-Scale Investigation on Acetaminophen Crystals with Stable and Metastable Phases by Frequency Modulation Atomic Force Microscopy in Aqueous Solution | |
| シンポジスト ： | ○Naritaka KOBAYASHI、Kazuki OKANO、Yoichiro MORI、Shun FUKUKITA、Mihoko MARUYAMA、Hiroaki ADACHI、Kazufumi TAKANO、Satoshi MURAKAMI、Hiroyoshi MATSUMURA、Tsuyoshi INOUE、Masashi YOSHIMURA、Yusuke MORI、Seiichiro NAKABAYASHI、Hiroshi YOSHIKAWA |
| 26G-ISMS18 | |
| Anti-inflammatory Flavan-dihydrochalcones with Unprecedented Carbon Skeletons from Daemonorops Draco | |
| Anti-inflammatory Flavan-dihydrochalcones with Unprecedented Carbon Skeletons from Daemonorops Draco | |
| シンポジスト ： | ○Ping-Chung KUO、Hsin-Yi HUNG、Tsong-Long HWANG、Tian-Shung WU |
| 26G-ISMS19 | |
| Development of a Fully Automated HPLC System (ASAPrepTM) Designed for Multiple Compound Purifications | |
| Development of a Fully Automated HPLC System (ASAPrepTM) Designed for Multiple Compound Purifications | |
| シンポジスト ： | ○Chie KUSHIBE、Katsuhiko MIWA、Hidetoshi TERADA、Yuji KATSUYAMA |
| 26G-ISMS20 | |
| Discovery of a Novel PDE10A Inhibitor as Highly Effective for Schizophrenia | |
| Discovery of a Novel PDE10A Inhibitor as Highly Effective for Schizophrenia | |
| シンポジスト ： | ○Yoichi KADOH、Takehiko MATSUMURA、Yoshihito TANAKA、Mitsuya HONGU、Haruko MIYOSHI、Mayumi KIMURA、Kei TAKEDOMI、Kenji OMORI、Jun KOTERA、Takashi SASAKI、Kiichi TANAKA、Keiko MIWA、Tamaki KOBAYASHI、Hiroyuki TANIGUCHI、Taketoshi ISHII、Yumi WATANABE、Haruna ITODA、Rikiya |
| 26G-ISMS21 | |
| Nucleic Acid Drugs Large Scale Manufacturing and Specification Assay– Equivalency Solid Phase versus AJIPHASE® and Oligonucleotide Sequences Confirmation for IND and NDA | |
| Nucleic Acid Drugs Large Scale Manufacturing and Specification Assay– Equivalency Solid Phase versus AJIPHASE® and Oligonucleotide Sequences Confirmation for IND and NDA | |
| シンポジスト ： | ○Satoshi INOUE、Hirokazu NANKAI、Emi SAITO、Hideaki SATO、Kazuhiko YUYAMA |
| 26G-ISMS22 | |
| Amycolamicin, a Novel Antibiotic as a Promising Candidate for Clostridium Difficile Infection: Antibacterial Activity, Mode of Action, and In Vivo Efficacy | |
| Amycolamicin, a Novel Antibiotic as a Promising Candidate for Clostridium Difficile Infection: Antibacterial Activity, Mode of Action, and In Vivo Efficacy | |
| シンポジスト ： | ○Yoshimasa ISHIZAKI、Kazushige SASAKI、Hideki HASHIZUME、Chigusa HAYASHI、Kunio INOUE、Hayamitsu ADACHI、Yoshiaki TAKAHASHI、Masayuki IGARASHI、Yoshio NISHIMURA、Yuzuru AKAMATSU、Akio NOMOTO、Masakatsu SHIBASAKI |
| 26G-ISMS23 | |
| Identification and Optimization of a Novel Series of Tetrahydroisoquinoline Derivatives as an Orally Active MGAT2 Inhibitor | |
| Identification and Optimization of a Novel Series of Tetrahydroisoquinoline Derivatives as an Orally Active MGAT2 Inhibitor | |
| シンポジスト ： | ○Tsuyoshi BUSUJIMA、Hiroaki TANAKA、Eiji MUNETOMO、Kiyokazu KITANO、Masako SAITO |
| 26G-ISMS24 | |
| Discovery of Novel Fluoroquinolone Antibiotics WFQ-101 and Its Optimization Study | |
| Discovery of Novel Fluoroquinolone Antibiotics WFQ-101 and Its Optimization Study | |
| シンポジスト ： | ○Tatsuya HIRANO、Tomohiko KINOSHITA、Daichi KAZAMORI、Satoshi INOUE、Kouji NISHIMURA、Asuka SAKURAI、Ayuka SASAKI、Yasuhiro KURAMOTO、Hirotaka AMANO、Akira YAZAKI |
| 26G-ISMS25 | |
| Anti-CTLA-4 Antibody scFv Producing Recombinant Bifidobacterium Secretes CTLA-4 Blocker Specifically Inside Hypoxic Tumor and Suppresses Tumor Growth in Syngeneic Mice Model | |
| Anti-CTLA-4 Antibody scFv Producing Recombinant Bifidobacterium Secretes CTLA-4 Blocker Specifically Inside Hypoxic Tumor and Suppresses Tumor Growth in Syngeneic Mice Model | |
| シンポジスト ： | ○Shiro KATAOKA、Koichiro SHIOYA、Li WANG、Tomio MATSUMURA、Hitomi SHIMIZU、Yasuyoshi KANARI、Yuji SEKI、Yuko SHIMATANI、Minoru FUJIMORI、Shun'ichiro TANIGUCHI |
| 26G-ISMS27 | |
| Design, Synthesis and Biological Evaluation of a Novel Series of Peripheral-selective Noradrenaline Reuptake Inhibitor, Part I -Lead Series Discovery and Biological Concept Validation- | |
| Design, Synthesis and Biological Evaluation of a Novel Series of Peripheral-selective Noradrenaline Reuptake Inhibitor, Part I -Lead Series Discovery and Biological Concept Validation- | |
| シンポジスト ： | ○Ikuo FUJIMORI、Tomoya YUKAWA、Taku KAMEI、Yoshihisa NAKADA、Nobuki SAKAUCHI、Masami YAMADA、Yusuke OHBA、Maiko TAKIGUCHI、Masako KUNO、Izumi KAMO、Hideyuki NAKAGAWA、Teruki HAMADA、Tomoko IGARI、Teruaki OKUDA、Satoshi YAMAMOTO、Tetsuya TSUKAMOTO、Yuji ISHICHI、Hiroyuki U |
| 26G-ISMS28 | |
| Design, Synthesis and Biological Evaluation of a Novel Series of Peripheral-selective Noradrenaline Reuptake Inhibitor, Part II -Lead Optimization with Avoiding P-gp Substrate and Genetic Polymorphism- | |
| Design, Synthesis and Biological Evaluation of a Novel Series of Peripheral-selective Noradrenaline Reuptake Inhibitor, Part II -Lead Optimization with Avoiding P-gp Substrate and Genetic Polymorphism- | |
| シンポジスト ： | ○Tomoya YUKAWA、Ikuo FUJIMORI、Taku KAMEI、Yoshihisa NAKADA、Nobuki SAKAUCHI、Masami YAMADA、Yusuke OHBA、Hiroyuki UENO、Maiko TAKIGUCHI、Masako KUNO、Izumi KAMO、Hideyuki NAKAGAWA、Yasushi FUJIOKA、Tomoko IGARI、Yuji ISHICHI、Tetsuya TSUKAMOTO |
| 26G-ISMS29 | |
| Ex Vivo Gene-manipulated Mature Adipocytes: Novel Gene Therapy Medicine for Sustained Protein Replacement Therapy of Variety of Intractable Diseases | |
| Ex Vivo Gene-manipulated Mature Adipocytes: Novel Gene Therapy Medicine for Sustained Protein Replacement Therapy of Variety of Intractable Diseases | |
| シンポジスト ： | ○Masayuki KURODA、Hideaki BUJO、Koutaro YOKOTE、Yasushi SAITO、Masayuki ASO |
| 26G-ISMS30 | |
| Application of Novel Highly Immunodeficient Mice for Patient Derived Xenograft (PDX) Model and Evaluation of Anticancer Therapy | |
| Application of Novel Highly Immunodeficient Mice for Patient Derived Xenograft (PDX) Model and Evaluation of Anticancer Therapy | |
| シンポジスト ： | ○Seiji OKADA、Kulthida VAETEEWOOTTACAHRN、Hiroki GOTO、Ryusho KARIYA |
| 26G-ISMS31 | |
| The Unbound Concentration of Multimodal Drugs in the Assay Medium Used in the Multi-electrode Array System for Cardiac Risk Assessment with iPS Cell-derived Cardiomyocytes | |
| The Unbound Concentration of Multimodal Drugs in the Assay Medium Used in the Multi-electrode Array System for Cardiac Risk Assessment with iPS Cell-derived Cardiomyocytes | |
| シンポジスト ： | ○Takashi YOSHINAGA、Raku SINKYO、Kiyomi KIKUCHI、Tomohiko TANIGUCHI、Yuko SEKINO、Kohei SAWADA |
| 26G-ISMS32 | |
| Discovery of ASP3026, a Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor | |
| Discovery of ASP3026, a Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor | |
| シンポジスト ： | ○Kazuhiko IIKUBO、Yutaka KONDOH、Itsuro SHIMADA、Takahiro MATSUYA、Kenichi MORI、Yoko UENO、Sadao KUROMITSU、Minoru OKADA |
| 26G-ISMS33 | |
| Immune Profiling with a New NGS-based Repertoire Analysis | |
| Immune Profiling with a New NGS-based Repertoire Analysis | |
| シンポジスト ： | ○Takaji MATSUTANI、Kazutaka KITAURA、Hiroshi YAMASHITA、Hitomi AYABE、Hiroyuki SATO、Yuichi MORITA、Tadasu SHINI、Ryuji SUZUKI |
| 26G-ISMS34 | |
| Cyclodextrin-based Supramolecular Drug Carriers and Active Pharmaceutical Ingredients | |
| Cyclodextrin-based Supramolecular Drug Carriers and Active Pharmaceutical Ingredients | |
| シンポジスト ： | ○Taishi HIGASHI、Keiichi MOTOYAMA、Hidetoshi ARIMA |
| 26G-ISMS36 | |
| Synthesis and Evaluation of Potent, Orally Available, Well-balanced EP2 and EP3 Dual Agonists | |
| Synthesis and Evaluation of Potent, Orally Available, Well-balanced EP2 and EP3 Dual Agonists | |
| シンポジスト ： | ○Akihiro KINOSHITA、Masato HIGASHINO、Koji YOSHIDA、Yoshiyuki ARATANI、Akito KAKUUCHI、Keisuke HANADA、Hiroyuki TAKEDA、Toshikiko NISHIYAMA、Hidekazu MATSUYA、Kazuyuki OHMOTO |
| 26G-ISMS37 | |
| Novel Development of Chemotherapy for Relapsed and Refractory AML Based on the Promising Functional Mechanism of Cytidine Analog, DFP-10917 | |
| Novel Development of Chemotherapy for Relapsed and Refractory AML Based on the Promising Functional Mechanism of Cytidine Analog, DFP-10917 | |
| シンポジスト ： | ○Masakazu FUKUSHIMA、Kenzo IIZUKA、Chung ZHANG、Cheng JIN、Kiyoshi ESHIMA |
| 26G-ISMS38 | |
| System-wide Temporal Characterization of the Phosphoproteome of Non-small-cell Lung Cancer Cells Treated with Erlotinib | |
| System-wide Temporal Characterization of the Phosphoproteome of Non-small-cell Lung Cancer Cells Treated with Erlotinib | |
| シンポジスト ： | ○Adachi JUN、Yuichi ABE、Maiko SHIMIZU、Marina KISHIDA、Ayako SATO、Takeshi TOMONAGA |
| 26G-ISMS39 | |
| Identification of WAC-224, a Novel Anticancer Quinolone as a Human Topoisomerase II Inhibitor | |
| Identification of WAC-224, a Novel Anticancer Quinolone as a Human Topoisomerase II Inhibitor | |
| シンポジスト ： | ○Tomonori YAMAGUCHI、Kenji ITOH、Taichi UESHIMA、Rumiko SHIMABARA、Yohei KAWAKUBO、Masayuki SATO、Junpei YAMASHITA、Tatsuya HIRANO、Akira YAZAKI |
| 26G-ISMS40 | |
| Lenvatinib Mesilate (LEN) Enhanced Antitumor Activity of a PD-1 Blockade Agent by Potentiating Th1 Immune Response | |
| Lenvatinib Mesilate (LEN) Enhanced Antitumor Activity of a PD-1 Blockade Agent by Potentiating Th1 Immune Response | |
| シンポジスト ： | ○Yu KATO、Xingfeng BAO、Shannon MACGRATH、Kimiyo TABATA、Yusaku HORI、Sho TACHINO、Mark MATIJEVICI、Yasuhiro FUNAHASHI、Junji MATSUI |
| 26G-ISMS41 | |
| Identification of Blood-based Gene Expression Biomarkers for Major Depressive and Bipolar Disorders | |
| Identification of Blood-based Gene Expression Biomarkers for Major Depressive and Bipolar Disorders | |
| シンポジスト ： | ○Seiji NAKAMURA、Hiroaki HORI、Yohei ISHIZAWA、Kenichi MATSUBARA、Ryo MATOBA、Hiroshi KUNUGI |
| 26G-ISMS42 | |
| Anti-Helicobacter Pylori Activity of a Novel Derivative of Intervenolin | |
| Anti-Helicobacter Pylori Activity of a Novel Derivative of Intervenolin | |
| シンポジスト ： | ○Tomokazu OHISHI、Toru MASUDA、Shun-ichi OHBA、Chigusa HAYASHI、Hikaru ABE、Masayuki IGARASHI、Takumi WATANABE、Daniel Ken INAOKA、Kiyoshi KITA、Masakatsu SHIBASAKI、Manabu KAWADA |
| 26G-ISMS43 | |
| Discovery of Novel 5,6,7,8-tetrahydro[1,2,4]Triazolo[4,3-a]Pyridine Derivatives asγ-secretase Modulators | |
| Discovery of Novel 5,6,7,8-tetrahydro[1,2,4]Triazolo[4,3-a]Pyridine Derivatives asγ-secretase Modulators | |
| シンポジスト ： | ○Takafumi TAKAI、Tatsuki KOIKE、Minoru NAKAMURA、Yasutaka HOASHI、Yoshihide TOMATA、Sachie MORIMOTO、Yuichi KAJITA、Toshiro YAMASHITA、Naohiro TAYA、Tetsuya TSUKAMOTO、Tomomichi WATANABE、Koji MURAKAMI、Tomoko IGARI、Makoto KAMATA |
| 26G-ISMS44 | |
| Regulatory Science for R&D Promotion of Innovative Pharmaceuticals* | |
| Regulatory Science for R&D Promotion of Innovative Pharmaceuticals* | |
| シンポジスト ： | Kazuhiko MORI、Takao YAMORI、○Toru KAWANISHI、Takao INOUE |